9. In allergic asthma, Th2 lymphocytes release cytokines, such as IL-4, -5 and -13, in response to allergen, resulting in recruitment of eosinophils, mast cells and CD4+ lymphocytes into the airways. As disease severity progresses and, in certain subsets of asthmatics, such as smokers and those with occupational asthma, a Th1 immune response can predominate with release of cytokines such as TNF-α and IL-8, resulting in recruitment of neutrophils to the airways. Uncontrolled inflammation can lead to structural changes in the airway walls - a process known as remodeling. This can lead to fixed airflow obstruction and worse clinical outcomes. Inhaled corticosteroids (ICSs) are the mainstay of anti-inflammatory therapy in asthma. However, many patients remain symptomatic despite high-dose therapy There is a need to develop new anti-inflammatory therapies for patients with asthma, either as an add-on therapy to corticosteroids or even as a replacement. (Cochrane Database)
10. Atopic or suspected Atopic Asthma are identified for nutritional intervention in accordance with the literature. (Experimental Parasitology 16 (3) 373-381 and British Journal of Dermatology 89 (5) 459-465)
11. Those with Atopy will increase their own production of enzyme when they improve their breath hold. (Increasing breath hold increases malic acid dehydrogenase a comparison of diving and non diving mammals comparative biochemistry and physiology: Molecular Biology 94 (3) 475 – 480)
12. Wheat ingestion in diet may be a contributory factor in atopy type asthma. This is due to the harvesting practices of wheat with combine harvesters. There is no enzymatic growth allowed on the wheat when harvested by a combine harvester. Avemar is recommended.
Emotional Implications of Asthma
13. Lung emotions according to Barral (DO) are fear of suffocation, fear of drowning, being locked up, commitment, oppression and dominating or being dominated.
Manipulation for Asthma
14. Manipulation of the spine can be appropriate in some cases because it has been shown to facilitate improvements in outcome measures in tandem with medical best care. (Gibbs AL. Chiropractic Co-management of Medically Treated Asthma. Clinical Chiropractic 8 (3) 140-144)
15. Improvements in breathing following manual therapy was the modal non musculoskeletal improvement reported in a multi-nation study. (Leboeuf-Yde C et al. Self Reported Non-musculoskeletal improvements following chiropractic intervention – a multi nation survey. JMPT 28 (5) 294-302.)
Self Control in Asthma
16. Gaining control of asthma can be sustainably achieved in a 6 month period resulting in less use of inhaled corticosteroids. Buteyko Method has shown to improve asthma symptoms without medication. (Cowie R. et al A Randomised Controlled Clinical Trial of the Buteyko Technique as an adjunct in the Management of Asthma. Respiratory Medicine (2008)102, 726–732)
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